Crimson Publishers-Investigations in Gynecology Research & Womens Health

In any surgical procedure, a suture is considered crucial. In the case of post-operative are the wound closure related to surgical procedure continues to pose a problem. Presently, Oxidized Regenerated Cellulose (ORC) is being commonly used in the absorption of hemostatic materials. But ORC medical suture product is not commercially available. It has been aimed to produce innovative braided suture by TEMPO-mediated Oxidation Regenerated Cellulose (TORC) so as to obtain a suture material having and perfect in mechanical properties. A circular braiding machine has been used to produce sutures from regenerated cellulose strands. The braiding is followed by TEMPO-mediated oxidation treatment as an option. Various investigation techniques that include ATR-FTIR, electrical conductivity, XRD analysis, physical properties and in vitro degradation properties have been used to characterize the sutures under various oxidation time. It has been further shown that the RC sutures have been oxidized ...

Cervical cancer is the fourth leading cause of cancer and cancer death among women worldwide [1]. According to the International Agency for Research on Cancer (IARC) in 2018, the global incidence is estimated at 570,000 new cases per year, of which more than 80% occur in developing countries [1]. In Morocco, the cervical cancer represents a major public health problem. It ranks second, after breast cancer in Moroccan women [2]. The incidence of cervical cancer remains high among women living with HIV. However, many studies have shown that this population has an increased risk of developing intraepithelial cervical neoplasia [3]. In the fight against cervical cancer, Morocco has a national cancer control programme under the aegis of the LALLA SALMA Foundation since 2006, thus enabling the creation of reference centers for screening and diagnosis of cervical cancer [4]. Women living with HIV often escape this program because of fear of stigmatization and disclosure of their HIV status. I...

Peripheral and central sensitizations are conditions of the nervous system that are characterized by increased tone and responsiveness, a lower threshold for the experience of pain and a tendency for pain to persist long after the original stimulus has ended [1]. The mechanism of the development of chronicity is under intense investigation involving a variety of important biochemical and sensitization processes. From a clinical perspective however, the situation can be summed up that pain per se, if not kept under control, may initiate the processes causing the transition from acute to chronic pain. Basic Investigations Investigations into the origins of central sensitization in particular, have focused on the role of continuous peripheral drive from the nociceptors (defined as neurons that are activated by noxious stimulation). It has been shown these nociceptors can become sensitized after being injured and develop a lower threshold for activation. Further, the persistence of affer...

Postmenopausal osteoporosis is a silent disease with not much of symptoms until fractures occur. It is characterized by low bone mineral density (BMD) and changes in bone microarchitecture that reduces bone strength and there is increase in risk of fractures [1]. After menopause, estrogen deficiency is the major contributing factor. Because of this there is an increase in RANK-ligand (RANKL) and a decrease in osteoprotegerin (OPG) secretion from osteoblasts. This imbalance induces fast bone loss, and thus there is increase in risk of fractures. WHO has identified osteoporosis as a major public health concern [2]. Osteoporosis is widely recognized as an important public health problem because of the significant morbidity, mortality and costs associated with its complications-namely fractures of the hip, spine, forearm and other skeletal sites [3]. The incidence of fragility fractures is highest among elderly white women, with one in every two women suffering an osteoporosis related frac...

Current State of Art Embryo Selection Techniques _ Crimson Publishers Current State of Art Embryo Selection Techniques by Cara Wessels* in Investigations inGynecology Research & Womens Health Assisted reproductive technologies (ARTs) have made many advancements since the birth of Louise Brown in 1978. Success rates have improved within the past four decades, but currently remain only between 40-60% successful and fertility treatments cost $12,000-$15,000 [1]. To improve pregnancy rates, two to three embryos are often transferred into the uterus of the patient or recipient in hopes of one surviving. This results in high fecundity, which is a current challenge ART is facing [2-4]. The practice of transferring multiple embryos into the uterus of non-litter bearing animals or humans is not the safest technique to the mother or fetus because it can increase likelihood of preterm labor, low birth weights, uterine growth restrictions, preeclampsia, gestational diabetes , place...