Crimson Publishers-Investigations in Gynecology Research & Womens Health

Herpes Simplex Encephalitis (HSE) is life-threatening viral encephalitis in pregnancy that significantly associated with poor outcomes in mother and infant. A 22-year-old 25 weeks pregnant woman presented with fever and seizure that was suspected to HSE. At first, MRI and Lumbar Puncture (LP) helped in the diagnosis, and however the PCR test confirmed HSE. What is interesting about this case is that the patient had no positive history of HSV before her pregnancy. From her hospital stay to confirming the lab test, she developed progressively worsening despite treating with early administration of acyclovir. Finally, she was successfully treated. No physical or psychological consequences remained. Later, she delivered via cesarean section and gave birth to a healthy infant. As soon as the HSE is suspected in pregnancy, the onset of early antiviral therapy reduces physical and psychosocial consequences. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000...

Introduction: South Africa has one of the highest rates of sexual violence against females in the world [1,2]. Residual outcomes among rape survivors in South Africa are complex, and include symptoms of depression, and post-traumatic stress (PTSS) [3,4] as well as physical and gynecological problems [5,6]. While South African rape survivors report physical and mental health symptoms [7]. We know little about the internal (i.e. self-management) and external (i.e. support from others) coping strategies that they use over time.   Objectives: This study conducted secondary analyses of South African female rape survivors who reported experiences of rape within six months of being interviewed and compared their physical and mental health, coping strategies, rape myths and social undermining of friends and families one year later. The goal is to foster a discussion of post-rape outcomes that may be utilized to develop recovery interventions for South African women rape survivors who may...

Psychological Health Status and Oral Health Outcomes of Pregnant Women: Practical Implications by Irosha Perera in Womens Health Journal_ Gynecology Open Access Journals Opinion Pregnancy marks an important milestone in the life cycle of a woman garnered by a milieu of physiological, psychological, emotional, social and even spiritual health needs [1]. Ensuring safe motherhoods and pregnancy outcomes for a healthy mother and a baby have become priorities for health policy makers and health care delivery models both in developed and developing country scenarios. Moreover, pregnancy denotes an opportune time for intergenerational investment in health outcomes. It is well known that physiological changes that are taking place during pregnancy could give rise to demanding psychological health concerns among pregnant women compounded by their social determinates such as i.e. level of education, marital status and satisfaction, level of income, parity, minority status, having heal...

Urgent Care of Fetal Heart Rate Bradycardia by Kazuo Maeda in Womens Health_Gynecology Open Access Journal Abstract As fetal bradycardia is the sign of fetal hypoxia, emergency early caesarean section is usually indicated in fetal heartrate (FHR) in the labor, while in some cases simple lateral posture is recommended. Infantile cerebral palsy is prevented, if novel hypoxia index is 24 or less. Hypoxia index, FHR score and FHR curve frequency spectrum are update progress in automated computerized FHR diagnosis. Keywords: FHR monitoring; Fetal bradycardia; Hypoxia index; FHR score; FHR frequency spectrum; Computer diagnosis Introduction As fetal heart rate decreases if fetal vagal nerve center is excited by the stimulation of low PaO2 lower than 50mmHg in fetal hypoxia, sudden transient or continuous fetal bradycardia, fetal hypoxic damage, particularly fetal brain damage followed by hypoxic ischemic encephalopathy (HIE) and infantile cerebral palsy in severe hypoxia, in ...

Cesarean Section Epidemic in Iranian Midwives by Somayeh M in Womens Health Journal Opinion In the last century, caesarean section (C/S) has played a positive role in settling pregnancy complications and reducing the fetal and maternal mortality, but a worrying issue in modern midwifery is the high rate of C/S. According to the World Health Organization, the C/S rate should not exceed 10-15% of all births in any part of the world, but published statistics in many parts of the world, especially in Iran, differed greatly from this ratio and are very higher. C/S is a major operation that has complications such as maternal death, hemorrhage, infection , need for blood transfusion, dense internal adhesions, thromboembolic, urinary retention, bladder injury, and anesthetic complication. Furthermore, an increase in the rate of C/S in a country may cause a high cost to the health system. In recent decades, it seems that there is a general tendency for C/S among both health care ...

An Assessment of the Effect of Team Building on Team Performance in Gutu District, Masvingo Province, 2010 by Pomerai KW in Womens Health Journal Abstract Introduction: Lack of team work is a major problem in civil service in Zimbabwe. Poor team work leads to reduced performance in a team. Gutu district performed very little for the past three years and a baseline survey showed lack of team work. This study aimed to assess the effectiveness of team building on team performance. Methods: A before and after quasi experimental study was conducted. District managers were study participants. A baseline survey was conducted to determine views on key leadership issues, such as convening meetings, managing conflict, planning and communication. Next, a five-day team building retreat was conducted in a secluded area away from the district. After the team building exercise, participants were observed for three months to assess improvement in planning, convening meeting...

Human Infertility is Disease. What People Should Know About Her? by Siniša Franjić in Womens Health Journal_ Gynecology Open Access Journal Abstract Infertility is an absence of clinical pregnancy after two years of trying to reach it. According to World Health Organization data, between 7% and 26% of people have problems with infertility. Medical assistance is sought by 50% of infertile couples, and only about 22% are subjected to treatment. Infertility is a disease which can be cure, and this fact gives hope to couples who want to become parents. Keywords: Infertility; Man; Woman; Medically assisted insemination Introduction While a number of couples use different methods to limit their fertility and prevent new life, on the other hand a number of them - and it is constantly growing - has only one desire: to acquire own child [1]. To accomplish this desire, them no price is too high. Own desires, social pressures, as well as scientific-technical optimism and prom...

Bilateral Gonadblastoma and Dysgerminoma in an 18-Year-Old Female Patient with 46xy, Sty Gene Mutation by Schmeink CE in Womens Health Journal Background: The need for prophylactic gonadectomy in XY gonadal dysgenesis patients is well known because of the risk of malignancy . However, the timing of surgery is not prescribed and in case of an unexpected finding like a dysgerminoma the need for additional treatment is controversial. Case: A 18-year-old adolescent with a 46XY disorder of sex development (DSD) and a SRY gene mutation underwent a laparoscopic gonadectomy . Pathology showed bilateral gonadoblastoma and dysgerminoma. Additional imaging showed no metastasis. After multidisciplinary consultation, expectant management was advised. In the first years of follow-up, there was no recurrence of disease. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000541.php For more Open access journals in Crimson publishers please click on the link https://crimsonpublishers.com/ F...

Domestic Violence Against Women: A Complex Issue in Pakistan by Rukhshanda Zarar in Womens Health Open access Journal Domestic Violence against women is widespread and complex issue in Pakistan. Nearly every woman practices domestic violence in her whole life. The aim of this paper is to aware, educate and inform the worse situation of domestic violence against women in Pakistan. This does not exist only in lower and middle class, but highly educated women also suffer because of male dominant society. It might be physical , sexual, or psychological violence. Our Pakistani culture , tradition, norms and values support this act. This is deeply believed in our society that women are inferior to men. This article focuses the worse situation of domestic violence against women in Pakistan. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000540.php For more Open access journals in Crimson publishers please click on the link https://crimsonpublishers.com/ For more articles in...

Management of a Rare Case of Post IVF Triplet Ectopic Pregnancy Post Bilateral Tubal Occlusion by Poonam Mishra in Womens Health_ Gynecology Open access journal Incidence of ectopic pregnancy after Invitro fertilization and embryo transfer (IVF-ET) in patients with prior bilateral tubal occlusion is negligible and if it occurs, it happens at unusual sites which are both difficult to diagnose as well as to treat. The possibility of early uterine rupture with life threatening haemorrhage is very high in such cases, therefore treatment of these pregnancies often require hysterectomy as a life saving measure. Our case of triplet lives ectopic pregnancy followed embryo transfer of three blastocysts. She had undergone laparoscopic bilateral proximal tubal occlusion 5 years ago. In this case, trans-abdominal ultrasound guided suction evacuation was attempted unsuccessfully. Hysteroscopy followed, which confirmed normal endometrial cavity with no gestational sac within it. Post ...

The Effect of Surgery Type on the Quality of Life in Breast Cancer Patients: A Mini Review by Kefayat Chaman Ara in Womens Health Journal Breast cancer is the most common women cancer around the world. The disease, its diagnosis and treatment impose considerable negative physical and psychosocial effects on the patients and severely threaten their quality of life. Surgical treatment with different types is the most used option for breast cancer treatment. In this mini-review we briefly reviewed the effects of different surgery types on the breast cancer patients ’ quality of life. Current evidence shows that breast preserving surgery saves patients’ quality of life more than other surgery types. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000536.php For more Open access journals in Crimson publishers please click on the link  https://crimsonpublishers.com/ For more articles in Gynecology Journal please click on the link  https://crimsonpublishers.com/igrwh...

Two Useful Safe Products for Maintaining Healthy Vagina and Prevention of Infection with Human Papilloma Virus leading to Carcinoma of Cervix by Talwar GP in Womens Health Journal We developed a Poly-herbal formulation named as BASANT, which has remarkable properties of inhibiting a wide spectrum of genital infections . It inhibits all WHO (World Health Organization) strains of N. gonorrhoeae including those strains resistant to Penicillin, Tetracycline. Nalidixic acid and Ciprofloxacin [1] it has pronounced inhibitory action against Candida glabarata, Candida albicans , and Candida tropicalis isolated from women with vulvovaginal candidacies, including strains resistant to azole drugs and amphotericin [1]. BASANT has inhibitory action on free as well as within cells contained Chlamydia trachomatis [2]. BASANT inhibits HIV-1 at the early stage of infection. What is more, it is effective against HIV strains employing both CCR5 and CXCR4 receptors for entry into blood cells. It is ef...

Effects of KRAS Gene Mutations in Gynaecological Malignancies by Ramakrishnan V in Gynecology Journal_ Gynecology Open access Journal Gynaecological disorders and malignancies affect the female reproductive system. Every woman in her life time suffers from gynaecological problem at some extent. The development and pathogenesis of gynaecological disorders is still remains unclear, several clinical and epidemiological studies have documented that they can be triggered by environmental, life-style, genetic factors and epigenetic alterations.The KRAS (Kristen rat sarcoma viral oncogene) gene is the commonly mutated oncogene. This gene provides instructions for making a protein called as K-Ras, which plays a vital role in cell division, differentiation and apoptosis. The frequency of mutations in this oncogene is highly reported in gynaecological cancers. This review highlights the common mutations observed in KRAS gene that is associated with breast, cervical, ovarian and endom...

The Pregnancy Microbiome: The Link Between Maternal Periodontitis and Adverse Pregnancy Outcomes: Opinion by  Irosha Rukmali Perera in Women health journal_ Gynecology Open access Journal The contagious environment of the oral cavity supports a complex microbial community. Accordingly, the oral cavity harbours the second most diverse microbial community in the body (being second only to the gut) with around 1000 species and many of them are uncultivated bacteria [1]. Humans depend on commensal bacteria for nutritive , immune modulation and maintaining health [2]. An array of physiological and pathological status such as the obesity and metabolic syndrome has been implicated for microbial changes in body sites termed as ‘dysbiosis’. Moreover, microbial changes could result in several body habitats such as the gut, oral cavity and vagina due to alterations in diet, environment, weight and hormones. Hence, significant microbial changes occur with regard to aforementioned body habitats...

Humanized GHR106 Monoclonal Antibody is a Biosimilar GnRH Antagonist by Gregory Lee in Gynecology journal_ Open access journal of Gynecology GHR106 is a monoclonal antibody generated against human GnRH receptor. The humanized forms of GHR106 exhibit almost identical biological properties to those of decapeptide GnRH antagonists such as Antide and Cetrorelix . The biosimilarity between these two GnRH receptor ligands was based on the studies of (1) binding affinity and specificity as well as immunohistochemical staining, (2) induced apoptosis to cancer cells and (3) effects of ligand- receptor bindings on gene regulations of cancer cells. Furthermore, the half-life of GHR106 antibody can be reduced from days to hours by means of antibody fragmentations to (Fab’)2 or Fab. The results of these biosimilar studies suggest that humanized GHR106 with IgG4 isotype can be utilized clinically with biosimilar functions as antibody -based GnRH antagonist except, with higher molecular size and lon...

Why Have We Failed? – An Analysis of the Origin of India’s Maternal & General Healthcare Problems by  Biswas SS in food science_ Gynecology Open access journal Many articles have been written on the topic of India’s pathetic and failing healthcare system. While each publication gave its own sets of views and advice, leaning on either the patient’s side or towards the doctor’s side, none whatsoever have addressed the issue of its origin. This article tries to look at the origin of the poor healthcare system and tries to find points which can be corrected and those that have gone beyond our control https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000523.php For more open access journals in Crimson publishers please click on the link  https://crimsonpublishers.com/ For more articles in Gynecology open access journals please click on the link  https://crimsonpublishers.com/igrwh/ Follow On Publons  :  https://publons.com/...

Endometrioid Borderline Tumor Related to Ovarian Endometriosis by  Anna Protasova in  Gynecology Research & Womens Health Endometrioid borderline tumor (EBT), also known as atypical proliferative endometrioid tumor, accounts for 0.2% of ovarian neoplasmas and 2-3% of borderline ovarian tumors. Very little is known about the prognosis and management of this entity. It is important to correctly diagnose these rare tumors in young women to assure proper treatment and to prevent mortality and preserve fertility. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000520.php For more open access journals in Crimson publishers please click on the link https://crimsonpublishers.com/ For more articles in Gynecology Research & Womens Health please click on the link https://crimsonpublishers.com/igrwh/ Follow On Publons  : https://publons.com/publisher/6342/crimson-publishers Follow On Linkedin : https://www.linkedin.com/company/crimsonpublishers