Crimson Publishers-Investigations in Gynecology Research & Womens Health

Intra Uterine Growth Restriction is a challenge to clinicians all over the world because no definitive treatment is available, and many empirical therapies are tried for treating the same. The present study was a multi-centric hospital based prospective observational study conducted in three tertiary care centers in Northern India on 200 patients with late onset IUGR and oligohydramnios. Sildenafil citrate 25mg 8 hourly was given till delivery. All the outcomes were noted and analyzed. After sildenafil therapy, 87 out 0f 90 patients with only IUGR, 35 out of 40 cases of oligohydramnios only and 64 out of 70 patients with IUGR & oligohydramnios both had marked improvement & 14 cases showed no improvement. From this study we concluded that adding sildenafil citrate in the treatment of IUGR and oligohydramnios can be a beneficial option. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000581.php Read More About Crimson Publishers: https://crimson...

Fibroadenoma and phyllodes tumor are fibroepithelial lesions, thus may have similar histopathological appearance and share overlapping clinical as well as radiological features. The distinction between these two lesions is clinically important as both lesions have different management. There is substantial overlap between fibroadenomas and phyllodes tumors. We present a similar case report of a 23 years-old female patient with classical radiological features of phyllodes tumor, which turned out to be a giant type of fibroadenoma on histopathology after surgical excision. Keywords: Giant fibroadenoma; Phyllodes; Mammography; Ultrasound; MRI Abbreviations: BIRADS: Breast Imaging-Reporting and Data System Introduction Fibroadenoma is a benign lesion, accounting for well over half of breast tumors, while phyllodes tumor have spectrum of diseases ranging from benign to malignant lesions, accounting for 1% of all breast neoplasms [1]. Fibroadenoma and phyllodes tumor are fibroepith...

Introduction: Urinary incontinence is a common problem with widespread human and social implication causing discomfort, shame and loss of self-confidence. It not only affects the quality of life but also has significant cost complications. Aim of the Study: To find out the effectiveness of kegel exercise, interferential therapy and transverse abdominis strengthening in treating patients having stress urinary incontinence. Methodology: A total of 50 subjects having stress urinary incontinence at least 6-month duration were recruited randomly. Group 1 experimental group was treated with kegel exercise, interferential therapy and transverse abdominis strengthening and Group 2 conventional group was treated with kegel exercise and transverse abdominis strengthening for five days/week for 4 weeks. Outcome Measures: Urinary incontinence questionnaire, modified oxford scale and transverse abdominis strength by modified sphygmomanometer. Measurements were taken before and at the end of...

Abstract Background: Cervical Diseases associated with Papillomavirus infection are one of the most pressing problems modern gynecology due to the high frequency of occurrence (in the structure gynecological morbidity - from 20 to 45%) and the ability to steady progression of the pathological process. A significant place in the structure of CM pathology is occupied by cervical intraepithelial neoplasia (CIN), which are often malignancy. Of particular importance are the issues of oncological transformation of the cervix in patients of reproductive age, taking into account the upcoming implementation of reproductive function. In Russia over the past 15 years, there has been an increase in the proportion of neglected cases of cervical cancer (cervical cancer), which ranks second (after breast cancer) in the structure of malignant tumors in reproductive age in women. Unfortunately, to date, the data of only an anamnesis, general clinical laboratory and instrumental met...

Mini Review Since most of the RNAs/proteins that support the initial phases of embryogenesis are accumulated during oocyte growth [1], knowledge about the effects of oocyte quality on embryo development plays a crucial role in the development of adequate assisted reproduction techniques. In this sense, understanding the requirements of oocytes recovered from different sized follicles is very important to optimize IVM and IVF of oocytes, which can have an excellent impact on the number of embryos produced in vitro. It will also allow analysis of the developmental potential of oocytes at different stages of development, the pattern of gene expression, the epigenetic modifications and the cytogenetic disorders in various domestic species, including humans [2]. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000567.php   Read More About Crimson Publishers: https://crimsonpublishers.com/

Abstract Ovarian granulosa cell tumors (GCT) are rare ovarian neoplasms. The main treatment for GCT is surgical. The volume of operation depends on the stage of the disease and the age of the patient. The possibility of maintaining fertility in patients of reproductive age in the early stages of the disease and the feasibility of lymphadenectomy are discussed. The positive effect of repeated cytoreductive operations for relapse was demonstrated. Role of chemotherapy in the treatment of GCT, due to the rarity of GCT and the late recurrence of the disease, is still not defined. Adjuvant chemotherapy is not shown to protect against relapse in patients with adult type (AGCT). Hormone therapy is considered to be a promising direction for the palliative treatment of AGCT relapses. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000566.php Read More About Crimson Publishers: https://crimsonpublishers.com/

Abstract Ovarian vein thrombosis (OVT) is a rare but potentially serious postpartum complication, which occurs in 0.05% to 0.18% of pregnancies and is diagnosed on the right side in 80% to 90% of the cases [1,2]. As OVT can mimic acute abdomen it should be considered in the differential diagnosis of postpartum acute abdomen [3]. We present a case of a 29-year-old female who presented a diffuse abdominal pain, fever and vomit on her third postpartum day. Her computed tomography demonstrated left ovarian vein repletion defect compatible with the presence of a thrombus. She was treated with enoxaparin and antibiotics, which lead to a resolution of the thrombus. Our case highlights the importance of prompt diagnosis and treatment of OVT in order to prevent morbidity and mortality. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000561.php Read More About Crimson Publishers:  https://crimsonpublishers.com/

  Abstract Uterine artery pseudoaneurysms (UAPs) are rare vascular lesions and may be life threatening if not diagnosed and properly treated. Tubo-ovarian abscess (TOA) represents an end stage process of pelvic inflammatory disease and the definitive therapy is surgery. We describe the case of a woman with a UAP after abdominal bilateral sapling-oophorectomy caused by a TOA. Six days later, she presented with sharp abdominal pain, and a Jackson-Pratt drain was filled with 70cc per hour. Selective uterine artery angiography demonstrated a UAP, and embolization was performed successfully. And we reviewed 10 cases of pseudoaneurysm after a gynecological operation, especially the first symptoms and diagnosis methods. In conclusion, UAP suspicion is required in the event of first symptoms such as vaginal spotting, abdominal discomfort/pain, fever, dizziness, etc. And, if it is suspected even slightly, an imaging works up should be conducted in a timely manner to quickly achieve diagnosi...

Abstract Background: There are few exploratory studies on Human Papillomavirus (HPV) infection and cervical cancer in indigenous populations. Because these women represent a very peculiar population in terms of habits and cultural rituals of its own, HPV infection and its related-oncogenesis potential could not denote the same progression characteristics as compared to the other populations commonly studied. The aim of this study was to evaluate 13 years of cervical cancer screening actions and assistance in the Xingu Indigenous Park, through cytological analysis and DNA-HPV molecular test. Methods: This is an observational, transversal and retrospective study conducted by data analysis of screening and control actions of uterine cervical HPV-associated lesions in the scope of the Xingu project supported by the Universidad Federal de São Paulo (UNIFESP), Brazil. The population studied consisted of indigenous, sexually active women, aged 11 years or older, belonging to sixteen ethni...

Abstract Objective: To compare between different uterine wall incision direction, vertical incision and transverse incision in abdominal myomectomy of intramural myoma regarding to complications.   Methods: The study were conducted on 60 patients attending the shatby University Maternity Hospital underwent abdominal myomectomy for a single site intramural myoma. They were randomly divided into vertical incision group (30 patient) and a transverse incision group (30 patient). The intra-opera- tive blood loss, uterine wound size. Results: We proved that there was no significant difference between both incision regarding intra-oper- ative blood loss, uterine incision size. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000556.php Read More About Crimson Publishers: https://crimsonpublishers.com/