Genetic Characteristics of Oocytes and Somatic Cells of Ovarian Follicles in Humans


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Since most of the RNAs/proteins that support the initial phases of embryogenesis are accumulated during oocyte growth [1], knowledge about the effects of oocyte quality on embryo development plays a crucial role in the development of adequate assisted reproduction techniques. In this sense, understanding the requirements of oocytes recovered from different sized follicles is very important to optimize IVM and IVF of oocytes, which can have an excellent impact on the number of embryos produced in vitro. It will also allow analysis of the developmental potential of oocytes at different stages of development, the pattern of gene expression, the epigenetic modifications and the cytogenetic disorders in various domestic species, including humans [2].

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