Crimson Publishers-Investigations in Gynecology Research & Womens Health

Introduction: The estimation of fetal weight is of paramount importance in the management of labor and delivery. The study was conducted to find usefulness of clinical estimation of fetal weight as it is useful for developing countries where ultrasonography facilities are unavailable in many areas. Aim: The study aimed at determining accuracy of fetal weight estimation clinically by Johnson’s formula and ultrasonographical by Hadlock’s method. Material & Methods: A descriptive study in the department of obstetrics and gynecology at a tertiary care hospital in western India was conducted between July 2017-June 2018 on pregnant patients with 37 to 40 weeks gestation after applying inclusion and exclusion criteria. Results: The study group consists of 260 subjects from urban, rural settings and different socio-economic classes. There was positive correlation between actual birth weight and Johnson’s formula weight (R=0.533, P= 0.000) as well as between actual birth weight and esti...

Herpes Simplex Encephalitis (HSE) is life-threatening viral encephalitis in pregnancy that significantly associated with poor outcomes in mother and infant. A 22-year-old 25 weeks pregnant woman presented with fever and seizure that was suspected to HSE. At first, MRI and Lumbar Puncture (LP) helped in the diagnosis, and however the PCR test confirmed HSE. What is interesting about this case is that the patient had no positive history of HSV before her pregnancy. From her hospital stay to confirming the lab test, she developed progressively worsening despite treating with early administration of acyclovir. Finally, she was successfully treated. No physical or psychological consequences remained. Later, she delivered via cesarean section and gave birth to a healthy infant. As soon as the HSE is suspected in pregnancy, the onset of early antiviral therapy reduces physical and psychosocial consequences. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000...

In any surgical procedure, a suture is considered crucial. In the case of post-operative are the wound closure related to surgical procedure continues to pose a problem. Presently, Oxidized Regenerated Cellulose (ORC) is being commonly used in the absorption of hemostatic materials. But ORC medical suture product is not commercially available. It has been aimed to produce innovative braided suture by TEMPO-mediated Oxidation Regenerated Cellulose (TORC) so as to obtain a suture material having and perfect in mechanical properties. A circular braiding machine has been used to produce sutures from regenerated cellulose strands. The braiding is followed by TEMPO-mediated oxidation treatment as an option. Various investigation techniques that include ATR-FTIR, electrical conductivity, XRD analysis, physical properties and in vitro degradation properties have been used to characterize the sutures under various oxidation time. It has been further shown that the RC sutures have been oxidized ...

Intra Uterine Growth Restriction is a challenge to clinicians all over the world because no definitive treatment is available, and many empirical therapies are tried for treating the same. The present study was a multi-centric hospital based prospective observational study conducted in three tertiary care centers in Northern India on 200 patients with late onset IUGR and oligohydramnios. Sildenafil citrate 25mg 8 hourly was given till delivery. All the outcomes were noted and analyzed. After sildenafil therapy, 87 out 0f 90 patients with only IUGR, 35 out of 40 cases of oligohydramnios only and 64 out of 70 patients with IUGR & oligohydramnios both had marked improvement & 14 cases showed no improvement. From this study we concluded that adding sildenafil citrate in the treatment of IUGR and oligohydramnios can be a beneficial option. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000581.php Read More About Crimson Publishers: https://crimson...

Abstract Disseminated Intravascular Coagulation (DIC), the most catastrophic obstetric acute emergency, is characterized by an inappropriate activation of coagulation & fibrinolytic system triggered by conditions like abruptio placentae & amniotic fluid embolism (release of thromboplastin intravascularly) or by diffuse endothelial damage as a result of pre-eclampsia. Clinical manifestation of severe bleeding and damaged coagulation profile are hallmarks of diagnosis, although histopathological demonstration of fibrin deposits is the pathognomonic feature of DIC. Understanding the basic pathophysiology, tackling the underlying etiological factor and replacement of the lost blood and specific components cover the principles of management of this condition. Keywords: DIC; FFP; Thromboplastin coagulation failure; Coagulopathy Abbreviations : DIC: Disseminated Intravascular Coagulation; HELLP: Hemolysis Elevated Liver Enzymes and Low Platelets Syndrome; IUFD: Intrauterine Fetal Dea...

One of the serious complications that are being experienced by women over many eras has been the issue of postpartum syndrome and the ways of coping with it. It is clear that many women can lose attention to their lives, their babies and their husbands. Actually, they become less happy and more stressful. Yet, this is not bound to the physicality of their beings, it is because of hormones. As is it is known that after childbirth, a dramatic drop in hormones (estrogen and progesterone) in women’s body may contribute to postpartum depression. Other hormones produced by mothers’ thyroid gland also may drop sharply-which can leave mother feeling tired, sluggish and depressed. Frankly, women need to feel emotionally supported in those hard times. Yet how can it be possible when they are fully confronted with the degenerated body image, inconvenient hormone rates and stressed mind after birth? Possibly they can be backed up by their husbands or other family members and they can get proper mo...

Cervical cancer is the fourth leading cause of cancer and cancer death among women worldwide [1]. According to the International Agency for Research on Cancer (IARC) in 2018, the global incidence is estimated at 570,000 new cases per year, of which more than 80% occur in developing countries [1]. In Morocco, the cervical cancer represents a major public health problem. It ranks second, after breast cancer in Moroccan women [2]. The incidence of cervical cancer remains high among women living with HIV. However, many studies have shown that this population has an increased risk of developing intraepithelial cervical neoplasia [3]. In the fight against cervical cancer, Morocco has a national cancer control programme under the aegis of the LALLA SALMA Foundation since 2006, thus enabling the creation of reference centers for screening and diagnosis of cervical cancer [4]. Women living with HIV often escape this program because of fear of stigmatization and disclosure of their HIV status. I...

Peripheral and central sensitizations are conditions of the nervous system that are characterized by increased tone and responsiveness, a lower threshold for the experience of pain and a tendency for pain to persist long after the original stimulus has ended [1]. The mechanism of the development of chronicity is under intense investigation involving a variety of important biochemical and sensitization processes. From a clinical perspective however, the situation can be summed up that pain per se, if not kept under control, may initiate the processes causing the transition from acute to chronic pain. Basic Investigations Investigations into the origins of central sensitization in particular, have focused on the role of continuous peripheral drive from the nociceptors (defined as neurons that are activated by noxious stimulation). It has been shown these nociceptors can become sensitized after being injured and develop a lower threshold for activation. Further, the persistence of affer...

Sociology appraising various dimensions of human life, will have a close look at the dependency of women on gynecology at current times. Many factors such as longer life expectancy, late marriage, urbanization, industrialization, curiosity for further rejuvenation and many more, have contributed to further tendency toward gynecology by women in modern time. Previously, and when science of gynecology had not advanced, women would easily die in young age. Women are exposed to more illnesses and health disorders as compared to men. Women at any age are anxious to keep on their beauty and body shape. Such a value highly attaches them to gynecologists. Modern gynecology originating in Western countries, gradually entered the developing countries with special reference to the richer ones. In modern time, gynecology has become a sort of tourism (Medical Tourism), in that, the well to do women go to other countries for special treatments. Sometimes and in many areas, specialties of gynecology ...

Introduction: South Africa has one of the highest rates of sexual violence against females in the world [1,2]. Residual outcomes among rape survivors in South Africa are complex, and include symptoms of depression, and post-traumatic stress (PTSS) [3,4] as well as physical and gynecological problems [5,6]. While South African rape survivors report physical and mental health symptoms [7]. We know little about the internal (i.e. self-management) and external (i.e. support from others) coping strategies that they use over time.   Objectives: This study conducted secondary analyses of South African female rape survivors who reported experiences of rape within six months of being interviewed and compared their physical and mental health, coping strategies, rape myths and social undermining of friends and families one year later. The goal is to foster a discussion of post-rape outcomes that may be utilized to develop recovery interventions for South African women rape survivors who may...

The SARS-CoV 2 pandemic is now responsible for over 48 million infections and one million deaths worldwide. Pandemics impact population growth not only by excessive mortality, but also by preventing births. In previous pandemics occurring in the 20 th and 21 st centuries, a trend towards birth rate reduction was observed 9 months later (Figure 1). After the 1918-20 HIN1 influenza pandemic, birth rates dropped by 5 to 15% in comparison to average rates before the pandemic [1]. This drop was related to higher death rates in pregnant patients (case fatality rate of 27%), as well as miscarriages and stillbirths (increased by 0.4% and 2.2% respectively as compared to prior average rates) [1,2]. A rebound in birth rates, however, occurred 1-2 years after this decline [3]. Moreover, several studies have shown that children born in 1919, and thus exposed to the H1N1 virus in utero, experienced worse health and socioeconomic outcomes in older ages than surrounding birth cohorts [4]. SARS-CoV ...

  There are perspectives to cure breast cancer, and the main strategy in that way is the exact estimation of tumor dissemination at diagnosis. It is well proved that disseminated tumor cells in the bone marrow are the most important prognostic factor in operable breast cancer [1]. Its prognostic role become visible at late periods after surgery (sometimes, 25 years). Taking in mind that women with breast cancer are around 60-year-old, one may see that the relapses arises usually after 80. It appears in brain, lung and other distant organs as hematologic metastases, and unfortunately, nothing is possible to do in the most of those cases, so the main reasons of deaths in breast cancer are distant metastases. Hematological dissemination of breast cancer takes place at very early stages of the diseases, sometimes even at carcinoma in situ [2]. The main reservoir of tumor cells in the organism is bone marrow [3,4]. Those cells survive for a long time and then wake up and come to some ...

Postmenopausal osteoporosis is a silent disease with not much of symptoms until fractures occur. It is characterized by low bone mineral density (BMD) and changes in bone microarchitecture that reduces bone strength and there is increase in risk of fractures [1]. After menopause, estrogen deficiency is the major contributing factor. Because of this there is an increase in RANK-ligand (RANKL) and a decrease in osteoprotegerin (OPG) secretion from osteoblasts. This imbalance induces fast bone loss, and thus there is increase in risk of fractures. WHO has identified osteoporosis as a major public health concern [2]. Osteoporosis is widely recognized as an important public health problem because of the significant morbidity, mortality and costs associated with its complications-namely fractures of the hip, spine, forearm and other skeletal sites [3]. The incidence of fragility fractures is highest among elderly white women, with one in every two women suffering an osteoporosis related frac...

Abstract Background: Cervical Diseases associated with Papillomavirus infection are one of the most pressing problems modern gynecology due to the high frequency of occurrence (in the structure gynecological morbidity - from 20 to 45%) and the ability to steady progression of the pathological process. A significant place in the structure of CM pathology is occupied by cervical intraepithelial neoplasia (CIN), which are often malignancy. Of particular importance are the issues of oncological transformation of the cervix in patients of reproductive age, taking into account the upcoming implementation of reproductive function. In Russia over the past 15 years, there has been an increase in the proportion of neglected cases of cervical cancer (cervical cancer), which ranks second (after breast cancer) in the structure of malignant tumors in reproductive age in women. Unfortunately, to date, the data of only an anamnesis, general clinical laboratory and instrumental met...

Why Have We Failed? – An Analysis of the Origin of India’s Maternal & General Healthcare Problems by  Biswas SS in food science_ Gynecology Open access journal Many articles have been written on the topic of India’s pathetic and failing healthcare system. While each publication gave its own sets of views and advice, leaning on either the patient’s side or towards the doctor’s side, none whatsoever have addressed the issue of its origin. This article tries to look at the origin of the poor healthcare system and tries to find points which can be corrected and those that have gone beyond our control https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000523.php For more open access journals in Crimson publishers please click on the link  https://crimsonpublishers.com/ For more articles in Gynecology open access journals please click on the link  https://crimsonpublishers.com/igrwh/ Follow On Publons  :  https://publons.com/...

Oral Condition in Pregnant Women with Various Types of Diabetes Mellitus by Grinenko Eleonora in Gynecology Research & Womens Health Background: In literature much attention is paid to connection of oral diseases in pregnant women with diabetes, because the course of pregnancy in patients with diabetes can adversely affect both the intrauterine development of fetus, and state of mother. It is proved that the frequency of the carious process and inflammatory periodontal diseases (gingivitis and periodontitis) significantly increase during pregnancy, and diabetes mellitus is an additional adverse factor. Aim: To study and compare dental status of pregnant women with different types of diabetes mellitus and without it using basic and additional clinical research methods, as well as method of periodontal liquid cytology. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000521.php For more open access journals in Crimson Publishers please click on th...

Intrauterine Contraceptive Device (IUCD-Cu T380a) Migration-A Case Report by  Subha Sivagami Sengodan in  Gynecology Research & Womens Health Background:  Though CU T was designed to prevent unwanted pregnancies, a number of complications are being reported. This may end up in asymptomatic course or present as an acute abdomen after migration into peritoneal cavity. Case:  Here we report a case of an intrauterine contraceptive device (IUCD-CU T380A)migration into the abdominal cavity. An open approach was used and the intrauterine contraceptive device was retrieved. https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000519.php For more open access journals in Crimson publishers please click on the link https://crimsonpublishers.com/ For more articles in Gynecology Research & Womens Health please click on the link https://crimsonpublishers.com/igrwh/ Follow On Publons  : https://publons.com/publisher/6342/crimson-publishers Follow ...