Crimson Publishers-Investigations in Gynecology Research & Womens Health

A 24-year-old woman at 41 weak gestational age underwent epidural anesthesia and normal vaginal delivery. After 7 days of delivery, patient referred to our hospital with severe headache, left paresthesia, and tonic-clonic seizure. During this period, the patient suffered a headache that was attributed to the epidural anesthetic. Radiologic assessments showed thrombosis at superior sagittal sinus. Cerebral Sinus Venous Thrombosis (CSVT) is a rare disease. The annual incidence is estimated to be about 5 per million, which is affected by age, sex, and areas. Pregnancy, postpartum, use of oral contraceptive and abortions are major risk factors. It is difficult to diagnose the disease from eclampsia during pregnancy and puerperium. Due to the high mortality rate of this disease, timely diagnosis and treatment should be considered. Treatment with anticoagulants should be done immediately. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.00058...

Highlights   a) Bladder and cervical rupture should be considered, after precipitated vaginal delivery. b) When there is gross hematuria, a urinary catheter should be inserted to monitor the hematuria and urine output. c) If the hematuria persists and other associated symptoms appear, cystography is a useful tool for determining the severity of the bladder injury and determining the cause. Abstract   Cases of bladder rupture have been rarely reported following vaginal childbirth. To the best of our knowledge, however, no cases of combined cervical laceration and bladder rupture have been reported to date. We present the first case of a 31-year-old woman with gestational diabetes who suffered a combined cervical laceration and bladder rupture after childbirth. Precipitated labor caused by oxytocin induction resulted in vaginal and cervical lacerations. The bladder rupture was confirmed by cystography. A team of obstetricians and urologists performed the laparotomy. The patien...

Introduction: The estimation of fetal weight is of paramount importance in the management of labor and delivery. The study was conducted to find usefulness of clinical estimation of fetal weight as it is useful for developing countries where ultrasonography facilities are unavailable in many areas. Aim: The study aimed at determining accuracy of fetal weight estimation clinically by Johnson’s formula and ultrasonographical by Hadlock’s method. Material & Methods: A descriptive study in the department of obstetrics and gynecology at a tertiary care hospital in western India was conducted between July 2017-June 2018 on pregnant patients with 37 to 40 weeks gestation after applying inclusion and exclusion criteria. Results: The study group consists of 260 subjects from urban, rural settings and different socio-economic classes. There was positive correlation between actual birth weight and Johnson’s formula weight (R=0.533, P= 0.000) as well as between actual birth weight and esti...

The coronavirus COVID-19 pandemic is having potentially disastrous consequences for women’s and girls’ health around the world. Global health officials are struggling to keep the COVID-19 pandemic from wreaking havoc on women’s health. With domestic violence and maternal mortality expected to rise as women lose access to critical health treatments and social support. With children out of school, growing care needs for older people, and overburdened health services, unpaid care work has increased. Women make about 70% of the global health workforce and are more likely to work in front-line positions like nurses, midwives, and community health workers, in particular workers in the medical field. They also make up the majority of health-care workers, such as nurses and therapists. As such, they provide cleaning, laundry, and catering services are more likely to come into contact with the virus. All public health preparedness and response strategies for COVID-19 must account for both direc...

Hospital acquired infection or “nosocomial infection” adversely affects both patients and hospitals. Impact of nosocomial infections ranges from increased length of hospital stay, emotional stress, disability, death of the patients as well as increased hospital cost for the patients and providers. Studies in India have reported nosocomial infection rates from 8% to 58 %. To combat these infections, hospital needs effective methods of disinfection and sterilization which has nowadays been centralized into a single department called Central Sterile Supply Department. In our study Outcome was measures by two parameters: a) User Satisfaction b) Microbial count It was found that in user satisfaction 70% of user end staff are satisfied with the services provided to them. In microbial count of different items sterilized showed that 89 % samples are sterile whereas 11% samples show growth of three different organisms e.g. Coagulase-negative staphylococci, Klebsilla and Act. Baumannii. ...

Herpes Simplex Encephalitis (HSE) is life-threatening viral encephalitis in pregnancy that significantly associated with poor outcomes in mother and infant. A 22-year-old 25 weeks pregnant woman presented with fever and seizure that was suspected to HSE. At first, MRI and Lumbar Puncture (LP) helped in the diagnosis, and however the PCR test confirmed HSE. What is interesting about this case is that the patient had no positive history of HSV before her pregnancy. From her hospital stay to confirming the lab test, she developed progressively worsening despite treating with early administration of acyclovir. Finally, she was successfully treated. No physical or psychological consequences remained. Later, she delivered via cesarean section and gave birth to a healthy infant. As soon as the HSE is suspected in pregnancy, the onset of early antiviral therapy reduces physical and psychosocial consequences. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000...

In any surgical procedure, a suture is considered crucial. In the case of post-operative are the wound closure related to surgical procedure continues to pose a problem. Presently, Oxidized Regenerated Cellulose (ORC) is being commonly used in the absorption of hemostatic materials. But ORC medical suture product is not commercially available. It has been aimed to produce innovative braided suture by TEMPO-mediated Oxidation Regenerated Cellulose (TORC) so as to obtain a suture material having and perfect in mechanical properties. A circular braiding machine has been used to produce sutures from regenerated cellulose strands. The braiding is followed by TEMPO-mediated oxidation treatment as an option. Various investigation techniques that include ATR-FTIR, electrical conductivity, XRD analysis, physical properties and in vitro degradation properties have been used to characterize the sutures under various oxidation time. It has been further shown that the RC sutures have been oxidized ...

Intra Uterine Growth Restriction is a challenge to clinicians all over the world because no definitive treatment is available, and many empirical therapies are tried for treating the same. The present study was a multi-centric hospital based prospective observational study conducted in three tertiary care centers in Northern India on 200 patients with late onset IUGR and oligohydramnios. Sildenafil citrate 25mg 8 hourly was given till delivery. All the outcomes were noted and analyzed. After sildenafil therapy, 87 out 0f 90 patients with only IUGR, 35 out of 40 cases of oligohydramnios only and 64 out of 70 patients with IUGR & oligohydramnios both had marked improvement & 14 cases showed no improvement. From this study we concluded that adding sildenafil citrate in the treatment of IUGR and oligohydramnios can be a beneficial option. Read More About This Article: https://crimsonpublishers.com/igrwh/fulltext/IGRWH.000581.php Read More About Crimson Publishers: https://crimson...

Abstract Disseminated Intravascular Coagulation (DIC), the most catastrophic obstetric acute emergency, is characterized by an inappropriate activation of coagulation & fibrinolytic system triggered by conditions like abruptio placentae & amniotic fluid embolism (release of thromboplastin intravascularly) or by diffuse endothelial damage as a result of pre-eclampsia. Clinical manifestation of severe bleeding and damaged coagulation profile are hallmarks of diagnosis, although histopathological demonstration of fibrin deposits is the pathognomonic feature of DIC. Understanding the basic pathophysiology, tackling the underlying etiological factor and replacement of the lost blood and specific components cover the principles of management of this condition. Keywords: DIC; FFP; Thromboplastin coagulation failure; Coagulopathy Abbreviations : DIC: Disseminated Intravascular Coagulation; HELLP: Hemolysis Elevated Liver Enzymes and Low Platelets Syndrome; IUFD: Intrauterine Fetal Dea...

One of the serious complications that are being experienced by women over many eras has been the issue of postpartum syndrome and the ways of coping with it. It is clear that many women can lose attention to their lives, their babies and their husbands. Actually, they become less happy and more stressful. Yet, this is not bound to the physicality of their beings, it is because of hormones. As is it is known that after childbirth, a dramatic drop in hormones (estrogen and progesterone) in women’s body may contribute to postpartum depression. Other hormones produced by mothers’ thyroid gland also may drop sharply-which can leave mother feeling tired, sluggish and depressed. Frankly, women need to feel emotionally supported in those hard times. Yet how can it be possible when they are fully confronted with the degenerated body image, inconvenient hormone rates and stressed mind after birth? Possibly they can be backed up by their husbands or other family members and they can get proper mo...

Cervical cancer is the fourth leading cause of cancer and cancer death among women worldwide [1]. According to the International Agency for Research on Cancer (IARC) in 2018, the global incidence is estimated at 570,000 new cases per year, of which more than 80% occur in developing countries [1]. In Morocco, the cervical cancer represents a major public health problem. It ranks second, after breast cancer in Moroccan women [2]. The incidence of cervical cancer remains high among women living with HIV. However, many studies have shown that this population has an increased risk of developing intraepithelial cervical neoplasia [3]. In the fight against cervical cancer, Morocco has a national cancer control programme under the aegis of the LALLA SALMA Foundation since 2006, thus enabling the creation of reference centers for screening and diagnosis of cervical cancer [4]. Women living with HIV often escape this program because of fear of stigmatization and disclosure of their HIV status. I...

Peripheral and central sensitizations are conditions of the nervous system that are characterized by increased tone and responsiveness, a lower threshold for the experience of pain and a tendency for pain to persist long after the original stimulus has ended [1]. The mechanism of the development of chronicity is under intense investigation involving a variety of important biochemical and sensitization processes. From a clinical perspective however, the situation can be summed up that pain per se, if not kept under control, may initiate the processes causing the transition from acute to chronic pain. Basic Investigations Investigations into the origins of central sensitization in particular, have focused on the role of continuous peripheral drive from the nociceptors (defined as neurons that are activated by noxious stimulation). It has been shown these nociceptors can become sensitized after being injured and develop a lower threshold for activation. Further, the persistence of affer...

Sociology appraising various dimensions of human life, will have a close look at the dependency of women on gynecology at current times. Many factors such as longer life expectancy, late marriage, urbanization, industrialization, curiosity for further rejuvenation and many more, have contributed to further tendency toward gynecology by women in modern time. Previously, and when science of gynecology had not advanced, women would easily die in young age. Women are exposed to more illnesses and health disorders as compared to men. Women at any age are anxious to keep on their beauty and body shape. Such a value highly attaches them to gynecologists. Modern gynecology originating in Western countries, gradually entered the developing countries with special reference to the richer ones. In modern time, gynecology has become a sort of tourism (Medical Tourism), in that, the well to do women go to other countries for special treatments. Sometimes and in many areas, specialties of gynecology ...

Introduction: South Africa has one of the highest rates of sexual violence against females in the world [1,2]. Residual outcomes among rape survivors in South Africa are complex, and include symptoms of depression, and post-traumatic stress (PTSS) [3,4] as well as physical and gynecological problems [5,6]. While South African rape survivors report physical and mental health symptoms [7]. We know little about the internal (i.e. self-management) and external (i.e. support from others) coping strategies that they use over time.   Objectives: This study conducted secondary analyses of South African female rape survivors who reported experiences of rape within six months of being interviewed and compared their physical and mental health, coping strategies, rape myths and social undermining of friends and families one year later. The goal is to foster a discussion of post-rape outcomes that may be utilized to develop recovery interventions for South African women rape survivors who may...

The SARS-CoV 2 pandemic is now responsible for over 48 million infections and one million deaths worldwide. Pandemics impact population growth not only by excessive mortality, but also by preventing births. In previous pandemics occurring in the 20 th and 21 st centuries, a trend towards birth rate reduction was observed 9 months later (Figure 1). After the 1918-20 HIN1 influenza pandemic, birth rates dropped by 5 to 15% in comparison to average rates before the pandemic [1]. This drop was related to higher death rates in pregnant patients (case fatality rate of 27%), as well as miscarriages and stillbirths (increased by 0.4% and 2.2% respectively as compared to prior average rates) [1,2]. A rebound in birth rates, however, occurred 1-2 years after this decline [3]. Moreover, several studies have shown that children born in 1919, and thus exposed to the H1N1 virus in utero, experienced worse health and socioeconomic outcomes in older ages than surrounding birth cohorts [4]. SARS-CoV ...

Appropriate antenatal care is proven to play a crucial role in ensuring good outcome of the mother and the baby. Good antenatal care ensures periodic assessment of growth and development of the baby, and supplementation of additional nutrition required for the mother. It also provides prompt recognition of any complication that befall pregnancy, one such dreaded complication being gestational diabetes mellitus. Gestational diabetes mellitus (GDM) is defined as the carbohydrate intolerance of varying severity with onset or first recognition in pregnancy. The prevalence of GDM in India is around 3.8-21%, and it is seen more in urban women. Physical environment, ethnicity, genetics, dietary patterns, lifestyle, obesity, family history of diabetes mellitus, and history of GDM in the previous pregnancy are independent risk factors for the development of GDM. Carbohydrate metabolism in pregnant women differs from the non-pregnant state, where there is an increased demand for metabolic fuel...

  There are perspectives to cure breast cancer, and the main strategy in that way is the exact estimation of tumor dissemination at diagnosis. It is well proved that disseminated tumor cells in the bone marrow are the most important prognostic factor in operable breast cancer [1]. Its prognostic role become visible at late periods after surgery (sometimes, 25 years). Taking in mind that women with breast cancer are around 60-year-old, one may see that the relapses arises usually after 80. It appears in brain, lung and other distant organs as hematologic metastases, and unfortunately, nothing is possible to do in the most of those cases, so the main reasons of deaths in breast cancer are distant metastases. Hematological dissemination of breast cancer takes place at very early stages of the diseases, sometimes even at carcinoma in situ [2]. The main reservoir of tumor cells in the organism is bone marrow [3,4]. Those cells survive for a long time and then wake up and come to some ...

Postmenopausal osteoporosis is a silent disease with not much of symptoms until fractures occur. It is characterized by low bone mineral density (BMD) and changes in bone microarchitecture that reduces bone strength and there is increase in risk of fractures [1]. After menopause, estrogen deficiency is the major contributing factor. Because of this there is an increase in RANK-ligand (RANKL) and a decrease in osteoprotegerin (OPG) secretion from osteoblasts. This imbalance induces fast bone loss, and thus there is increase in risk of fractures. WHO has identified osteoporosis as a major public health concern [2]. Osteoporosis is widely recognized as an important public health problem because of the significant morbidity, mortality and costs associated with its complications-namely fractures of the hip, spine, forearm and other skeletal sites [3]. The incidence of fragility fractures is highest among elderly white women, with one in every two women suffering an osteoporosis related frac...

Fibroadenoma and phyllodes tumor are fibroepithelial lesions, thus may have similar histopathological appearance and share overlapping clinical as well as radiological features. The distinction between these two lesions is clinically important as both lesions have different management. There is substantial overlap between fibroadenomas and phyllodes tumors. We present a similar case report of a 23 years-old female patient with classical radiological features of phyllodes tumor, which turned out to be a giant type of fibroadenoma on histopathology after surgical excision. Keywords: Giant fibroadenoma; Phyllodes; Mammography; Ultrasound; MRI Abbreviations: BIRADS: Breast Imaging-Reporting and Data System Introduction Fibroadenoma is a benign lesion, accounting for well over half of breast tumors, while phyllodes tumor have spectrum of diseases ranging from benign to malignant lesions, accounting for 1% of all breast neoplasms [1]. Fibroadenoma and phyllodes tumor are fibroepith...

Introduction: Urinary incontinence is a common problem with widespread human and social implication causing discomfort, shame and loss of self-confidence. It not only affects the quality of life but also has significant cost complications. Aim of the Study: To find out the effectiveness of kegel exercise, interferential therapy and transverse abdominis strengthening in treating patients having stress urinary incontinence. Methodology: A total of 50 subjects having stress urinary incontinence at least 6-month duration were recruited randomly. Group 1 experimental group was treated with kegel exercise, interferential therapy and transverse abdominis strengthening and Group 2 conventional group was treated with kegel exercise and transverse abdominis strengthening for five days/week for 4 weeks. Outcome Measures: Urinary incontinence questionnaire, modified oxford scale and transverse abdominis strength by modified sphygmomanometer. Measurements were taken before and at the end of...